Examples include (1) an in-vivo reporter system for detecting estrogenic compounds using a transgenic marine medaka strain carrying the choriogenin (chg) promoter-GFP transgene (the technology was then commercialised as part of the environmental and food safety consultancy service in a Hong Kong-based biotechnology company), (2) development of the H295R steroidogenesis assay as an in-vitro screen for EDCs that interfere estrogen and testosterone production (this assay has become part of the OECD framework for the Testing and Assessment of Endocrine Disrupting Chemicals) and (3) development of real-time PCR assays for quantifying estrogen-induced gene expression (e.g., vitellogenin, vtg and estrogen receptor, er) in the native Australian oyster species, the Sydney rock oyster Saccostrea glomerata. Previously, my co-workers and I have developed sensitive molecular bioassays for environmental monitoring and risk assessment of compounds affecting sex hormone signalling and synthesis in both vertebrate and invertebrate systems. Overall, my research covers both basic science aimed at understanding the fundamental mechanisms of environmental toxicity and applied science concerned with the development of diagnostic tools for assessing and monitoring environmental toxicity and health impacts. In particular, I am interested in (1) understanding the molecular mechanisms of endocrine disruption caused by hypoxia and environmental chemicals, (2) developing bioassays for the screening and detection of endocrine-disrupting chemicals (EDCs) and (3) developing environmental DNA (eDNA) survey techniques to monitor aquatic wildlife populations. My primary research interests are in the molecular toxicology of environmental stressors and chemicals. Currently, I am a Senior Lecturer and Deputy Head of School (Teaching and Learning) in the School of Environmental and Life Sciences (SELS), College of Engineering, Science and Environment (CESE). Rudolf Wu, I continued to work in the same institution as a Lecturer until joining the University of Newcastle in 2009. After my postdoctoral training with Prof. In recognition of his contributions to medicine and the community, the University has resolved to confer upon Professor Richard Yu Yue Hong the degree of Doctor of Social Sciences honoris causa.I received my PhD from City University of Hong Kong in 2002. At present, he is the Chairman of the Higher Physician Training Committee, leading a revision exercise to implement changes in the Annual and Exit Examination for Higher Physician Trainees to ensure fairness, transparency and accountability. Just as the Hong Kong College of Physicians continues to benefit from Professor Yu's wise counsel, so indeed does Hong Kong society as a whole, as he persists in his lifelong quest to raise the quality of medical education, hospital services and the medical sector overall. He has served as a member of the Hospital Governing Committee of the Ruttonjee and Tang Shiu Kin Hospitals (1992-2002), and the Queen Mary Hospital and Tsan Yuk Hospital (since 2003). He was the Founding Honorary Secretary of the Hong Kong College of Physicians (1986-1995), its Vice-President for Education (1993-1995), and then its President (1998-2004). Professor Yu is a Fellow of the College of Physicians in Hong Kong, the three Royal Colleges of Physicians in UK and Australia, and of the Academies of Medicine of Hong Kong and Singapore. Professor Yu is currently Honorary Professor of the Department of Medicine at HKU, and of the Department of Medicine and Therapeutics at the Chinese University of Hong Kong he is also an Honorary Consultant Physician at the Ruttonjee and Princess Margaret Hospitals. Professor Yu went into private practice in 1973, but continued to teach in the Department as Honorary Clinical Lecturer and later as Honorary Clinical Associate Professor. Returning to HKU, he then held the posts of Lecturer and Senior Lecturer in the Department of Medicine, and completed his MD degree in 1972. Professor Richard Yu Yue Hong graduated from HKU with an MBBS degree in 1958, after which he completed his clinical training at Queen Mary Hospital and his research at University College Hospital, London, where he was awarded a PhD in 1966.
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